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Zinc Protoporphyrin
CAS No. 15442-64-5
Zinc Protoporphyrin ( Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9 )
Catalog No. M23667 CAS No. 15442-64-5
Zinc Protoporphyrin is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 49 | In Stock |
|
| 10MG | 63 | In Stock |
|
| 25MG | 123 | In Stock |
|
| 50MG | 219 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameZinc Protoporphyrin
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NoteResearch use only, not for human use.
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Brief DescriptionZinc Protoporphyrin is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity.
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DescriptionZinc Protoporphyrin is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity.
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SynonymsZn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorHuman Endogenous Metabolite;Reactive Oxygen Species
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Research Area——
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Indication——
Chemical Information
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CAS Number15442-64-5
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Formula Weight626.0
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Molecular FormulaC34H32N4O4Zn
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (79.87 mM; Need ultrasonic);H2O:< 0.1 mg/mL (insoluble)
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SMILESOC(CCC1=C(C=C2[N]3=C4C(C)=C2CCC(O)=O)[N-]([Zn+2]35[N]6=C7C=C(C(C=C)=C8C)[N-]5C8=C4)C(C=C6C(C=C)=C7C)=C1C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs. 2019 Apr 13;17(4).
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