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Zinc Protoporphyrin

CAS No. 15442-64-5

Zinc Protoporphyrin ( Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9 )

Catalog No. M23667 CAS No. 15442-64-5

Zinc Protoporphyrin is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Zinc Protoporphyrin
  • Note
    Research use only, not for human use.
  • Brief Description
    Zinc Protoporphyrin is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity.
  • Description
    Zinc Protoporphyrin is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-cancer activity.
  • Synonyms
    Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite;Reactive Oxygen Species
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    15442-64-5
  • Formula Weight
    626.0
  • Molecular Formula
    C34H32N4O4Zn
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (79.87 mM; Need ultrasonic);H2O:< 0.1 mg/mL (insoluble)
  • SMILES
    OC(CCC1=C(C=C2[N]3=C4C(C)=C2CCC(O)=O)[N-]([Zn+2]35[N]6=C7C=C(C(C=C)=C8C)[N-]5C8=C4)C(C=C6C(C=C)=C7C)=C1C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs. 2019 Apr 13;17(4).
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